Numerous immunological benefitsTherapeutic Indications:Maximum bioavailability with black pepper:-Curcuma has very low bioavailability, essentially due to its rapid glucuronidation;-The protection of curcuma from this metabolic conversion can be achieved to improve its bioavailability;-Black pepper is an intestinal and hepatic inhibitor of glucuronidation, and its concomitant administration increases curcuma's bioavailability by 11 times.AntimicrobialCurcuma extracts show inhibition of the growth of a number of bacteria, parasites, fungi, and viruses.Anti-InflammatoryIts anti-inflammatory properties are attributed to its regulatory capacity at the level of inflammatory transition factors, cytokines, redox status, protein kinases, and enzymes, all of which promote inflammation.It has been shown to reduce the expression of inflammatory markers, such as NF-k B, COX-2, 5-LOX, macrophage inflammatory protein-1 alpha, adhesion molecules, and C-reactive protein.Anti-carcinogenicCurcuma has demonstrated the ability to inhibit carcinogenesis at 3 stages: initiation, promotion, and tumor progression. It also has the capacity to suppress the activity of various mutagens and carcinogens.Gastrointestinal protectionCurcuma constituents inhibit intestinal spasms, as well as increase the secretion of gastrin, secretin, and pancreatic enzymes.HepatoprotectiveThe hepatoprotective effect of curcuma essentially stems from its antioxidant property and ability to decrease the formation of pro-inflammatory cytokines. One of the curcumin salts also has the ability to exert choleretic effects, increasing the excretion of bile salts, cholesterol, and bilirubin.Cardiovascular ProtectionThe positive effects of curcuma on Cardiovascular Health include decreased levels of cholesterol and triglycerides, decreased susceptibility to LDL lipid peroxidation, and inhibition of platelet aggregation.Immunity ImprovementCurcuma improves localized immunity by increasing the number of B cells and T helper cells, as well as overall immunity.AntioxidantCurcuma, as well as curcumin, demonstrate potent antioxidant activity, comparable to vitamin C and E. Studies have shown the effect of curcuma at the level of endothelial heme oxygenase-1, a protein known as a stress inducer. It has the ability to neutralize free radicals and increase glutathione levels.Composition:Per capsule:Curcuma (equivalence) – 10,000mg;Curcuma (containing at least 95% curcumin) – 350mg;Curcuma (extract 5:1) – 150mg;Black Pepper – 5mg;Vitamin C – 80mg (100% NRV*);Zinc – 10mg (100% NRV*).Per 2 capsules:Curcuma (equivalence) – 20,000mg;Curcuma (containing at least 95% curcumin) – 700mg;Curcuma (extract 5:1) – 300mg;Black Pepper – 10mg;Vitamin C – 160mg (200% NRV*);Zinc – 20mg (200% NRV*).NRV* - Nutrient Reference Value.Ingredients:Curcuma longa (curcuma; root extract containing at least 95% curcumin), bulking agent; microcrystalline cellulose, Curcuma longa (Curcuma; dry root extract 5:1), gelatin, l-ascorbic acid, zinc oxide, anti-caking agent: magnesium stearate, Piper nigrum (Black Pepper; dry fruit extract), anti-caking agent: silicon dioxide.Dosage and Administration:Take 1 capsule daily, preferably during breakfast. If necessary, you may take 2 capsules daily.Presentation:Pack of 60 capsulesWarnings:Store in a cool, dry place, away from light.Do not exceed the recommended daily intake.Avoid the product if you have an allergy or sensitivity to any of the ingredients.If you are pregnant, breastfeeding, taking any pharmaceutical specialty, or suffering from any illness, consult your doctor or health professional before taking this supplement.Food supplements should not be used as a substitute for a varied diet and a healthy lifestyle.Keep out of reach of children.
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