Menopause is the cessation of ovarian function that occurs around the age of 50, after which ovulation, fertilization, and menstruation no longer occur. This means that women going through this phase are no longer fertile. Menopause is not a disease and, as such, cannot be avoided. It is popularly known as the critical age. During menopause, many hormonal changes occur, mainly due to the decrease in estrogen (the main female sex hormone). Thus, women in this post-menopausal period are at high risk of heart disease and osteoporosis. The appearance of various symptoms directly linked to this period is characteristic, such as vaginal dryness, resulting from a lack of estrogen, or hot flashes and decreased libido, caused by other more complex hormonal changes. Natural supplementation is presented as an extraordinarily efficient alternative, as it is a source of phytoestrogens, substances chemically related to estrogen that thus naturally contribute to the relief of symptoms linked to the entire menopausal phase. OPTIFEMME ONE-A-DAY from Nutriflor is available in the form of LipidCapsTM (capsules with liquid content) - an innovation that offers greater bioavailability, more efficacy, and faster absorption by the body. Physiological action of each ingredient: - Soy, Glycina max L. The small globular seeds of soy represent one of the highest vegetable nutritional potentials. It contains about 35% protein (twice as much as meat), possessing all essential amino acids; these include caseins, whose composition is similar to milk, lipids, and about 30% carbohydrates. Soy is a food of great energetic value, anti-asthenic, remineralizing, and a factor of nutritional balance. It can be consumed cooked, as flour, raw, or sprouted, in the form of milk and even cheese. The oil it produces, commonly used in food, is rich in polyunsaturated fatty acids, proving effective in reducing blood cholesterol levels. - What are the nutritional secrets that these soy seeds hold for today's woman? Many researchers are unanimous in stating that their most beneficial components are a group of nutrients called Isoflavones, of which two stand out: genistein and daidzein. They have a remarkable antioxidant action, as they stimulate the production of Superoxide Dismutase (SOD), which is also another admirable antioxidant. In addition to being antioxidants, all Isoflavones are converted in the body into compounds with a physiological action identical to that of estrogens, the hormones responsible for women's feminine characteristics. Isoflavones are, therefore, phytoestrogens that help regulate estrogen levels in women. This estrogenic activity may be the main reason why genistein and other Isoflavones help protect against breast cancer, according to a study conducted by Dr. David T. Zava, Ph. D. of the Cancer Research Division of the California Public Health Foundation in Berkeley. Research on the benefits of soy Isoflavones has excited researchers due to the simplicity of their message: a simple food can help prevent diseases related to menopause and the symptoms associated with this condition, namely in reducing hot flashes. Many doctors are recommending soy Isoflavones as a safe and effective alternative to relieve menopausal symptoms, protect the heart, and maintain bone health, without increasing the risk of cancer or producing blood clots. In fact, many of the most experienced and famous scientists specializing in women's health are calling soy "the perfect alternative" to HRT. The OPTIFEMME ONE-A-DAY formula has one of the highest concentrations of isoflavones available on the market, providing maximum potency in phytoestrogens. - Lifenol, Humulus lupulus L. Lifenol is a new and completely natural hop extract obtained from the cones of the leaves and is characterized by a strong phytoestrogenic power. Its action is related to its high standardized content of prenylflavonoids, being the only hop extract that reduces the discomfort associated with menopause. Two clinical trials using the Kupperman index demonstrated the effectiveness of Lifenol in menopausal symptoms, particularly hot flashes, after 6 to 8 weeks of taking the supplement. - Pueraria lobata (Kudzu) The root and flowers of Kudzu have been used in traditional Chinese medicine for over 2500 years to treat different pathologies, such as migraine, hypertension, pain, and ankylosis of the neck and shoulders, but also to relieve menopausal symptoms. Kudzu is used as an ingredient in preparations for pathologies affecting women in menopause such as osteoporosis, coronary artery disease, and hormone-dependent carcinomas. The scientific basis for its action may be its activity as a natural phytoestrogen by containing phytochemicals called isoflavones. Isoflavones present in the Kudzu root, such as puerarin, daidzein, and genistein, bind and activate the estrogen beta receptor. Kudzu phytoestrogens can serve as an alternative to hormone replacement therapy. The isoflavone tectorigenin found in Kudzu can help stop the replication and proliferation of cancer cells and tumors and, therefore, help prevent and treat cancer. For example, 50mg of raw Kudzu root ingested daily relieved hot flashes and night sweats in perimenopausal Thai women, according to a study published in September 2007 in the "Journal of the Medical Association of Thailand"; and 100mg of Kudzu isoflavones taken daily improved cognitive function in postmenopausal women. The Kudzu extract used in the OPTIFEMME One-a-day formula provides 50mg of isoflavones per dose. - Cimicifuga racemosa (Black cohosh) Cimicifuga extract contains triterpene glycosides (actein, 27-deoxyactein, cimicifugoside, cimiracemoside A), flavonoids, particularly the isoflavone formononetin, phenolic acids (fucinol acid), volatile oils, tannins, salicylic acid, and isoferulic acid. The constituents formononetin (isoflavone) and the triterpene 27-deoxyactein are classified as phytoestrogens. It is believed that the effect of Cimicifuga is the result of the complex synergism of the components. The mechanism of action of Cimicifuga is not fully understood; some publications suggest action on estrogen receptors. The pharmacological effects on menopausal symptoms are justified by the negative feedback action on estrogen receptors, which will reduce luteinizing hormone (LH) levels. This reduction is responsible for the slowing down of symptoms. Research focuses mostly on the estrogenic activity of the plant. It is classified as a hormonal modulator. The phytoestrogens present in the rhizomes have a slight binding effect to estrogen receptors. The isoferulic acid constituent has an anti-inflammatory effect and reduces muscle spasm. Salicylic acid characterizes the anti-inflammatory and analgesic properties of the plant. Standardized extracts (in triterpene glycosides) have been shown to improve menopausal and premenopausal symptoms in clinical studies. - Discorea opposita (Wild Yam) Chinese Wild Yam (Wild Yam from China) contains Diosgenin, a phytohormone very similar to progesterone. Its richness in saponins and the fact that these can be industrially converted into products similar to cortisone, estrogens, and progesterone gives this plant a special status regarding hormonal problems associated with conditions such as menopause. The extract of Discorea opposita used in the OPTIFEMME One-a-day formula provides a high content of Diosgenin, 40mg per daily dose. - Angelica sinensis (Dong Quai) Known as female Ginseng, this plant is very rich in phytoestrogens and is therefore used for various menstrual problems and, specifically, as a regulator of menstrual disorders associated with menopause. In addition, it also has benefits in preventing cardiovascular diseases including hypertension. The use of a concentrated 5:1 extract of Angelica sinensis in the OPTIFEMME One-a-day formula provides approximately 500mg of the plant per dose. Complex of highly bioavailable plants that synergistically contribute to women's well-being during menopause: - Melissa officinalis L. (Lemon Balm) Lemon Balm is a plant where we find several active constituents that act synergistically, such as: triterpenic acids, flavonoids, and phenol-acids. More than 70 components have been isolated from its essential oil to date, to which the recognized antispasmodic properties of the plant are attributed. Lemon Balm thus has a very important sedative action, possessing sleep-inducing capabilities while acting as an analgesic to combat various types of nervous disorders (insomnia, melancholy, hysteria, and even nervous stomach pains). - Salvia officinalis L. (Sage) Sage leaves have antioxidant, bactericidal, choleretic, astringent, antispasmodic, and anti-exudative properties. The emmenagogue virtues of this plant are attributed to constituents with estrogenic effects; an antigonadotropic activity may also be added. Among other applications, this plant is indicated for the relief of menopausal symptoms such as profuse sweating. - Lepidium meyenii (Maca) The Maca plant root, commonly found in the Andes region, has shown beneficial effects on menopausal symptoms and anti-inflammatory action. The plant's root has often been used in the folk medicine of Andean peoples to combat anemia, infertility, depression, to maintain female hormonal balance, and to relieve menopausal symptoms. A study by Meissner et al evaluated the effects of Maca on climacteric symptoms of women with early menopause and compared them to a placebo. The results showed favorable effects of Maca supplementation, with a significant increase in well-being, higher energy levels, and fewer episodes of muscle numbness, headaches, and reduced night sweats. After eight months, the beneficial effects were even more pronounced in women who used Maca compared to the placebo group. According to researchers, Maca can thus be an excellent treatment alternative. - Vitex agnus-castus L. (Chaste Tree) This plant is rich in essential oils (monoterpenes and sesquiterpenes), flavonoids (including acacistin), and iridoid glycosides (including aucubin and agnuside). It promotes hormonal balance by stimulating the secretion of luteinizing hormone (LH), opposes the release of follicle-stimulating hormone (FSH), and increases progesterone levels; balancing the estrogen/progesterone ratio inhibits FSH secretion and stimulates LH secretion, shifting the estrogen/progesterone ratio in favor of progesterone. Chaste Tree thus helps regulate the female reproductive system and normalize hormonal imbalances, thereby contributing to the relief of menopausal symptoms. Vitamin complex: - Vitamin B6 (Pyridoxine) Vitamin B6 is known as the mood vitamin, due to its beneficial effect on the central nervous system. It promotes the adequate synthesis of nucleic acids, also being necessary for the manufacture of antibodies and red blood cells. It is often considered the "woman's friend" vitamin, as, among its various actions, it helps alleviate the side effects of hormone replacement, namely, it helps regulate estrogen levels in the body, alleviating the discomfort caused by its excess or lack. It is also one of the essential vitamins for calcium fixation, so important at this stage of life. As Vitamin B6 is a water-soluble vitamin, its excess is eliminated in the urine. The vitamin B complex is not stored in the body and must be renewed regularly through whole foods or supplements. Its presence in the body ensures good assimilation of proteins and lipids. - Vitamin E (D-Alpha-Tocopherol) This is a fat-soluble vitamin with antioxidant properties, which contributes to fighting free radicals. In this way, Vitamin E helps cellular structures to be better oxygenated, making them more resistant to fatigue.
Ingredients
Per daily dose:
Dioscorea opposita, Wild Yam: 564mg;
(Diosgenin): 90mg;
Glycine max, Soy: 250mg;
(Pure Isoflavones): 100mg;
Enriched Evening Primrose Oil: 200mg;
(GLA): 40mg;
Angelica sinensis, Dong Quai: 100mg;
(plant, root): 500mg;
Melissa officinalis, Lemon Balm: 40mg;
(Rosmarinic Acid): 1.2mg;
Salvia officinalis, Sage: 40mg;
(Rosmarinic Acid): 1.2mg;
Eleutherococcus senticosus, Siberian Ginseng: 33mg;
(Eleutherosides): 2.6mg;
Humulus lupulus, Hops: 24mg;
Vitex agnus-castus, Chaste Tree (fruit): 20mg;
Vitamin E (D-alpha-tocopherol acetate): 20mg;
Vitamin B6 (Pyridoxine hydrochloride): 10mg;
Salvia officinalis, Sage: 0.1mg
Instructions for use
Take 2 capsules a day, 1 in the morning and 1 at night.
Warning: Women undergoing treatment with estrogenic drugs should consult their doctor beforehand; Not recommended in cases of hyperestrogenism, malignant arterial hypertension, paroxysmal tachycardia, febrile states, myocardial infarction, circadian rhythm disorders, hypothyroidism, renal failure, estrogen-dependent breast tumors, hyperfolliculinemia.
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